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Addressing Trauma as a Health Risk
Clinicians at UCSF are taking on trauma as more than just a social issue. They are addressing how it has a staggering impact on a person’s health.
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UCSF, UC Hastings Launch Innovative Masters Program to Meld Health and Law
UCSF and UC Hastings College of the Law have combined their expertise to offer a new degree program: the Masters of Science program in Health Policy and Law, which begins classes in August.
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Bruce Alberts Named American Association for Cancer Research Fellow
Bruce Alberts has been named one of the 11 newly elected fellows of the American Association for Cancer Research.
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Mark Ryder: Bringing Magic to the Classroom
Periodontal disease is no fun, but that doesn’t mean learning about it can’t be.
For more than 30 years, Mark Ryder, DMD, a professor in the School of Dentistry’s Department of Orofacial Sciences, has been devoted to engaging his students during long lectures. His trick: Performing magic routines to illustrate complex scientific concepts.
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Berger, Bluestone Named to White House Cancer Moonshot Expert Panel
Mitchel Berger and Jeff Bluestone have been named to a Blue Ribbon Panel of scientific experts, cancer leaders and patient advocates that will help to guide the National Cancer Moonshot Initiative.
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Langley Porter Clinic Cornerstone Laid 75 Years Ago
On April 5, 1941, a crowd all assembled to witness the laying of the cornerstone of California's first modern neuropsychiatric institute.
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MASALA Study Examines South Asian Heart Disease Risks
To keep a person's heart healthy, clinicians recommend avoiding risk factors such as smoking or excessive weight gain. But one risk factor, which cannot be changed, is being South Asian.
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Big Papi's ballpark tour: Tracking David Ortiz's farewell season
Big Papi's ballpark tour: Tracking David Ortiz's farewell season
The Tourette International Collaborative Genetics (TIC Genetics) study, finding the genes causing Tourette syndrome: objectives and methods
Tourette syndrome (TS) is a neuropsychiatric disorder characterized by recurrent motor and vocal tics, often accompanied by obsessive-compulsive disorder and/or attention-deficit/hyperactivity disorder. While the evidence for a genetic contribution is strong, its exact nature has yet to be clarified fully. There is now mounting evidence that the genetic risks for TS include both common and rare variants and may involve complex multigenic inheritance or, in rare cases, a single major gene.
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Bifactor latent structure of ADHD/ODD symptoms: predictions of dual-pathway/trait-impulsivity etiological models of ADHD
Mothers' and fathers' ratings of ADHD-IN, ADHD-HI, and ODD symptoms in a community sample of 4,658 children and adolescents (53% female) from Brazil, Thailand, and the US were used to evaluate the measurement models.
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Evidence for linkage and association of GABRB3 and GABRA5 to panic disorder
Panic disorder (PD) is a debilitating anxiety disorder characterized by episodes of intense fear with autonomic and psychological symptoms that lead to behavioral impairment. A convergence of genetic and biological evidence implicates gamma-aminobutyric acid type A receptor subunits on chromosome 15q12 as candidate genes for PD. This study investigated 120 Caucasian, multiplex PD pedigrees using regional microsatellites (chr15q11-13) and found support for linkage (logarithm of odds (LOD) ⩾2), with a prominent parent-of-origin effect.
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Community-based harm reduction substance abuse treatment with methamphetamine-using men who have sex with men
Harm reduction approaches endeavor to assist individuals with avoiding the most detrimental consequences of risk taking behaviors, but limited research has documented the outcomes of harm reduction substance abuse treatment. In total, 211 methamphetamine-using men who have sex with men (MSM) enrolled in two outcome studies of substance abuse treatment programs that were implementing an evidence-based, cognitive-behavioral intervention (i.e., the Matrix Model) from a harm reduction perspective.
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Factors predicting development of opioid use disorders among individuals who receive an initial opioid prescription
Prescription drug abuse in the United States and elsewhere in the world is increasing at an alarming rate with non-medical opioid use, in particular, increasing to epidemic proportions over the past two decades. It is imperative to identify individuals most likely to develop opioid abuse or dependence to inform large-scale, targeted prevention efforts.
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Reducing risk for illicit drug use and prescription drug misuse: High school gay-straight alliances and lesbian, gay, bisexual, and transgender youth
Previous research suggests that lesbian, gay, bisexual, and transgender (LGBT) youth are at elevated risk for using illicit drugs and misusing prescription drugs relative to heterosexual youth. Previous research also indicates that LGBT youth who attend high schools with a gay-straight alliance (GSA) report having fewer alcohol problems and lower levels of cigarette smoking. The present study investigates whether the absence of a GSA is associated with risk for illicit drug use and prescription drug misuse in a sample of 475 LGBT high school students (M age=16.79) who completed an online survey.
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Reliability of functional magnetic resonance imaging activation during working memory in a multi-site study
Multi-site neuroimaging studies offer an efficient means to study brain functioning in large samples of individuals with rare conditions; however, they present new challenges given that aggregating data across sites introduces additional variability into measures of interest. Assessing the reliability of brain activation across study sites and comparing statistical methods for pooling functional data are critical to ensuring the validity of aggregating data across sites.
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Facilitating culture-centered communication between health care providers and veterans transitioning from military deployment to civilian life
To describe returning veterans' transition experience from military to civilian life and to educate health care providers about culture-centered communication that promotes readjustment to civilian life.
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Clues to maintaining calorie restriction? Psychosocial profiles of successful long-term restrictors
To combat the obesity epidemic, interventions and treatments often recommend low-calorie dieting. Calorie restriction (CR) as a weight intervention, however, is often unsuccessful, as most people cannot sustain the behavior.
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Does abortion reduce self-esteem and life satisfaction?
This study aims to assess the effects of obtaining an abortion versus being denied an abortion on self-esteem and life satisfaction.
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Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position
Cortical GABAergic interneurons have essential roles for information processing and their dysfunction is implicated in neuropsychiatric disorders. Transcriptional codes are elucidating mechanisms of interneuron specification in the MGE (a subcortical progenitor zone), which regulate their migration, integration, and function within cortical circuitry.
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Hippocampal volume is inversely related to PTSD duration
Numerous imaging studies have reported smaller hippocampal volumes in patients with PTSD. To investigate whether decreased hippocampal volume is associated with PTSD chronicity, independent of age, we used hierarchical linear regression to examine the relationship between PTSD duration (estimated from the amount of time that had elapsed since the traumatic event; mean=17 years; range=6-36 years) and hippocampal volume, adjusting for age and other factors.
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