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The Diamondbacks' road woes reached 22 straight games with Wednesday's 13-7 loss to the Giants, tying the 1963 New York Mets and the 1943 Philadelphia Athletics for the longest road losing streak since 1900.

Mets ace Jacob deGrom left his start on Wednesday against the Cubs after three innings because of right shoulder soreness, the team said.

New York Yankees ace Gerrit Cole said he struggled gripping the ball during his start Wednesday against Toronto and urged MLB to "continue to talk with us" amid the league's foreign-substance crackdown.

Third baseman Alex Bregman left with a strained left quadriceps against the Rangers on Wednesday.

The Phillies will be without second baseman Jean Segura for at least three weeks with a Grade 1 left groin strain, while slugger Bryce Harper is day-to-day with lower back tightness after both were injured Tuesday.

Mets ace Jacob deGrom left his start on Wednesday against the Cubs after three innings because of right shoulder soreness, the team said.

Through injuries, replacements and all kinds of residual 2020 weirdness, the White Sox have persevered on their way to becoming perhaps baseball's best team.

Rays pitcher Rich Hill said Wednesday that the MLBPA "dropped the ball" when it came to this week's announcement from Major League Baseball about new rules on grip-enhancing substances.

New York's No. 1 starter is off to one of the greatest starts ever. Keep up with deGrom's record pace, most amazing numbers and where things could go from here.

Forget the trade deadline. Boston could soon be adding the biggest missing piece in this year's pennant race.

Jose Abreu, Trevor Bauer, Corey Seager and Shohei Ohtani are the nominees for Best MLB Player at the 2021 ESPYS. Cast your vote today.

Bryce Harper left the Phillies' loss to the Dodgers on Tuesday night because of lower back tightness, while Jean Segura exited with an apparent groin injury.

After missing three straight games with left hamstring tightness, outfielder Cody Bellinger was placed on the 10-day injured list on Tuesday prior to the Los Angeles Dodgers' home game vs. the Philadelphia Phillies.

Bryce Harper left the Phillies' game against the Dodgers on Tuesday night after the fourth inning because of lower back tightness.

After missing three straight games with left hamstring tightness, outfielder Cody Bellinger was placed on the 10-day injured list on Tuesday prior to the Los Angeles Dodgers' home game vs. the Philadelphia Phillies.

Chicago Cubs star Kris Bryant was hit by a pitch in the first inning of Tuesday's game against the New York Mets and left with a bruised right hand.

Oakland A's skipper Bob Melvin will remain at the helm for at least one more season. The club picked up his contract option for 2022.

Tampa Bay Rays right-hander Tyler Glasnow has a partially torn ulnar collateral ligament and a flexor tendon strain, the team said Tuesday.

Speaking from experience -- and from the heart -- Boston manager Alex Cora on Tuesday addressed his Red Sox pitching staff about suspensions and the MLB rule changes on foreign substances, saying "you don't want to go through that."

The Nationals placed Max Scherzer on the 10-day injured list Tuesday with a groin injury.