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San Diego Padres third-base coach Matt Williams has been diagnosed with colon cancer and will be away from the team for an undisclosed period of time.

Angels catcher Logan O'Hoppe, the team's top prospect, said it was "super humbling" to be starting Thursday's opener against the A's.

The Phillies acquired outfielder Cristian Pache from the A's on Wednesday and placed first baseman Rhys Hoskins on the 60-day injured list.

Rangers center fielder Leody Taveras will start the season on the injured list while still recovering from a strained oblique.

Milwaukee Brewers right-hander Adrian Houser will start the season on the injured list with groin tightness and is expected to miss three weeks.

Check out how to watch some of the week's biggest MLB games, like Opening Day's White Sox-Astros showdown, on ESPN.

The use of a pitch clock shaved 26 minutes off spring training games this year as MLB is set to use it for the first time in regular-season games Thursday.

Can the Padres go all the way? Will Ohtani win MVP? Our experts make their predictions for the baseball season.

Our crew breaks down their favorite values in division, pennant, World Series and awards futures ahead of the 2023 baseball season.

Our baseball betting glossary will help get you prepared for the 2023 MLB season.

Yankees stars such as Aaron Judge and Gerrit Cole have been impressed by 21-year-old Anthony Volpe's talent and demeanor and believe he's ready for the pressure of being the franchise's youngest starting shortstop since Derek Jeter.

The Guardians and second baseman Andres Gimenez have reached an agreement on a contract extension.

Brewers infielder Keston Hiura, who was designated for assignment Monday, was outrighted to the team's Triple-A affiliate after he cleared waivers.

For the first time, MLB The Show will insert some of the greatest Negro League greatest players -- from Satchel Paige to Jackie Robinson -- into the 2023 edition of the game as playable characters.

Shohei Ohtani is expected to make a record $65 million for the 2023 season including endorsements, according to Forbes, making the Angels' two-way standout MLB's highest-paid player.

Who will rule -- and stumble -- this season? It's time to get up to speed as baseball returns.

Sergio Romo retired as a Giant just the way he wanted, pitching one final time for the team he helped to win three World Series championships and then calling it a career Monday night.

Cleveland Guardians right-hander Triston McKenzie has been shut down due to a strain of his right teres major muscle and could miss up to eight weeks

Philadelphia catcher J.T. Realmuto was ejected Monday from a spring training game against Toronto for an awkward ball exchange that followed a pitch-clock violation.

Second baseman Nico Hoerner and the Chicago Cubs are in agreement on a three-year, $35 million contract extension, sources told ESPN, locking up the team's most productive player last season for an extra season before he was due to hit free agency.