Feed aggregator
Facilitating culture-centered communication between health care providers and veterans transitioning from military deployment to civilian life
To describe returning veterans' transition experience from military to civilian life and to educate health care providers about culture-centered communication that promotes readjustment to civilian life.
Categories: News
Clues to maintaining calorie restriction? Psychosocial profiles of successful long-term restrictors
To combat the obesity epidemic, interventions and treatments often recommend low-calorie dieting. Calorie restriction (CR) as a weight intervention, however, is often unsuccessful, as most people cannot sustain the behavior.
Categories: News
Does abortion reduce self-esteem and life satisfaction?
This study aims to assess the effects of obtaining an abortion versus being denied an abortion on self-esteem and life satisfaction.
Categories: News
Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position
Cortical GABAergic interneurons have essential roles for information processing and their dysfunction is implicated in neuropsychiatric disorders. Transcriptional codes are elucidating mechanisms of interneuron specification in the MGE (a subcortical progenitor zone), which regulate their migration, integration, and function within cortical circuitry.
Categories: News
Hippocampal volume is inversely related to PTSD duration
Numerous imaging studies have reported smaller hippocampal volumes in patients with PTSD. To investigate whether decreased hippocampal volume is associated with PTSD chronicity, independent of age, we used hierarchical linear regression to examine the relationship between PTSD duration (estimated from the amount of time that had elapsed since the traumatic event; mean=17 years; range=6-36 years) and hippocampal volume, adjusting for age and other factors.
Categories: News
Decreased smoking disparities among Vietnamese and Cambodian communities
Since 1964, smoking prevalence in the United States has declined because of nationwide intervention efforts. However, smoking interventions have not been implemented uniformly throughout all communities. Some of the highest smoking rates in the United States have been reported among Southeast Asian men, and socioeconomic status has been strongly associated with smoking.
Categories: News
Major progress towards elucidating brain wiring diagrams
Systematic comparison of adeno-associated virus and biotinylated dextran amine reveals equivalent sensitivity between tracers and novel projection targets in the mouse brain.
Categories: News
Interneurons from embryonic development to cell-based therapy
Many neurologic and psychiatric disorders are marked by imbalances between neural excitation and inhibition. In the cerebral cortex, inhibition is mediated largely by GABAergic (γ-aminobutyric acid-secreting) interneurons, a cell type that originates in the embryonic ventral telencephalon and populates the cortex through long-distance tangential migration.
Categories: News
Association of alcohol use biomarkers and cognitive performance in veterans with problematic alcohol use and posttraumatic stress disorder
The authors conducted a study of alcohol use biomarkers and cognitive performance among 85 veterans with problematic alcohol use and posttraumatic stress disorder (PTSD). All analyses were adjusted for demographics, depression, anxiety, and PTSD symptoms. Elevated levels of aspartate aminotransferase were associated with worse performance on the Trail Making Test Part A and Hopkins Verbal Learning Test. Two other biomarkers were not associated with any neurocognitive measures.
Categories: News
Proteomic analysis of saliva in HIV-positive heroin addicts reveals proteins correlated with cognition
The prevalence of HIV-associated neurocognitive disorders (HAND) remains high despite effective antiretroviral therapies. Multiple etiologies have been proposed over the last several years to account for this phenomenon, including the neurotoxic effects of antiretrovirals and co-morbid substance abuse; however, no underlying molecular mechanism has been identified. Emerging evidence in several fields has linked the gut to brain diseases, but the effect of the gut on the brain during HIV infection has not been explored.
Categories: News
Decision making and prostate cancer screening
This article presents an overview of the challenges that men encounter in making decisions about prostate cancer screening, including complex affective and cognitive factors and controversies in the interpretation of the evidence on prostate cancer screening. Shared decision making involving patient decision aids are discussed as approaches that can be used to improve the quality of prostate cancer screening decisions, including a close alignment between a man's values, goals, and preferences and his choice about screening.
Categories: News
Cytokine gene variations associated with subsyndromal depressive symptoms in patients with breast cancer
This study explored the relationships between variations in cytokines genes and depressive symptoms in a sample of patients who were assessed prior to and for six months following breast cancer surgery. Phenotypic differences between Resilient (n = 155) and Subsyndromal (n = 180) depressive symptom classes, as well as variations in cytokine genes were evaluated.
Categories: News
Smoking cessation outcomes among sexual and gender minority and nonminority smokers in extended smoking treatments
Sexual and gender minority individuals (i.e., lesbian, gay, bisexual, and transgender [LGBT]) have a higher smoking prevalence than nonminority individuals. There is limited evidence of smoking abstinence success in nontailored smoking treatments among LGBT smokers.
Categories: News
Emergence of context-dependent variability across a basal ganglia network
Context dependence is a key feature of cortical-basal ganglia circuit activity, and in songbirds the cortical outflow of a basal ganglia circuit specialized for song, LMAN, shows striking increases in trial-by-trial variability and bursting when birds sing alone rather than to females. To reveal where this variability and its social regulation emerge, we recorded stepwise from corticostriatal (HVC) neurons and their target spiny and pallidal neurons in Area X.
Categories: News
Cardiorespiratory fitness and cognitive function in middle age: the CARDIA study. - PubMed - NCBI
To investigate whether greater cardiorespiratory fitness (CRF) is associated with better cognitive function 25 years later.
Categories: News
Association between schizophrenia symptoms and neurocognition on mobility in older adults with schizophrenia
Older persons with schizophrenia develop problems associated with aging, such as poor mobility, at more rapid rates than people without serious mental illness. Decrements in mobility contribute to poor health outcomes. Impaired neurocognitive function and psychiatric symptoms are central aspects of schizophrenia. The purpose of this study was to determine the association between neurocognitive impairment and schizophrenia symptoms to mobility in older adults with schizophrenia.
Categories: News
Change in inflammatory markers and cognitive status in the oldest-old women from the Study of Osteoporotic Fractures
To determine the association between interleukin-6 (IL-6), IL-6 soluble receptor (sR), and soluble tumor necrosis factor receptor-1 (sTNF-R1) and cognitive status in the oldest-old women.
Categories: News
Retromer mediates a discrete route of local membrane delivery to dendrites
A fundamental and still largely unresolved question is how neurons achieve rapid delivery of selected signaling receptors throughout the elaborate dendritic arbor. Here we show that this requires a conserved sorting machinery called retromer.
Categories: News
Cognitive training in mental disorders: update and future directions
This article reviews the conceptual basis, definitions, and evolution of cognitive training approaches for the treatment of mental disorders.
Categories: News
The emergency department social work intervention for mild traumatic brain injury (SWIFT-Acute): a pilot study
To determine acceptability and preliminary effectiveness of Emergency Department (ED) Social Work Intervention for Mild Traumatic Brain Injury (SWIFT-Acute) on alcohol use, community functioning, depression, anxiety, post-concussive symptoms, post-traumatic stress disorder and service use.
Categories: News