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For teams watching their budgets and willing to accept some risk, these 12 players could yield big payoffs.

Manny Machado's free-agent tour continued Wednesday afternoon in the Bronx, where he met with the second of his three suitors, the Yankees.

Major League Baseball, its players' association and the Cuban Baseball Federation reached an agreement that will allow players from the island nation to sign big league contracts without defecting.

Seattle announced a new 25-year naming rights deal on Wednesday, so the Mariners will play at T-Mobile Park beginning next year.

The new GM says the Mets are now the favorites to win their division. We examine if a division crown is an actual possibility or hyperbole from Brodie Van Wagenen.

The Brewers, Rays and Twins are perpetually a couple of bad deals from a crisis. But each has learned to use the newfangled free-agent market to its advantage.

From increased velocity to the rise of shifts, recent advancements have all favored pitching over hitting. Now a new wave of offense-focused minds is out to level the playing field.

Matt Harvey will be changing leagues for the first time in his major league career, agreeing to a one-year deal with the Angels worth a reported $11 million.

As rumors swirl about potential blockbuster deals for Miami's All-Star catcher, we examine how excited you should be if your team is in the Realmuto mix.

Study, led by UCSF, raises intriguing questions about whether the biology of low-risk prostate cancer in black men is distinct from that of other ethnicities. 

Andrew McCutchen admits that he's in decline, but says he knows what he's still capable of doing and is "looking forward" to hitting at Philadelphia's Citizens Bank Park.

New GM Brodie Van Wagenen on Tuesday introduced Wilson Ramos, the fourth All-Star to join the Mets since Van Wagenen was hired in late October, and touted the revamped team as the division favorite.

Infielder Daniel Descalso, who hit .237 with 22 doubles for Arizona last season, has agreed to a two-year deal with the Cubs.

Penny Marshall, one of the top-grossing female directors in Hollywood who produced "A League of Their Own" and was a passionate sports fan, has died at age 75.

Former Yankee Carlos Betran told ESPN's Enrique Rojas that he has been named special adviser to GM Brian Cashman. Beltran, who shares an agent with free agent shortstop Manny Machado, played for New York from 2014-16.

The Minnesota Twins will retire Joe Mauer's No. 7 jersey next season, moving swiftly with to honor the six-time All-Star who retired after a 15-year major league career.

The health headlines of 2018 captured our attention and impacted our lives in myriad ways. So what's next in 2019, for UCSF and beyond? You tell us.

Photos from across UCSF from 2018.

From sensory processing disorder to how CRISPR is being explored to bring new treatments to patients, these are the stories that most engaged our readers in 2018.

In the year since announcing an ambitious, $5 billion fundraising campaign, UCSF has seen record-breaking generosity from its supporters, inspired by faculty-led ideas to tackle some of the toughest problems in health and science.