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Dustin Pedroia's goal isn't merely to come back from his knee injury, but to remain healthy enough to contribute for the Red Sox for the entire season.

Brett Gardner won a World Series with the Yankees in his second season in 2009, but New York hasn't reached the World Series since and Gardner called it "a disappointing 10 years" on Thursday.

Longtime Boston Globe baseball writer Nick Cafardo has died after collapsing at the team's spring training ballpark.

The Los Angeles Dodgers will honor pitching great Don Newcombe by adding a commemorative No. 36 patch to their uniforms this season.

Rockies star Nolan Arenado, who will be a free agent next winter if he doesn't reach an agreement on a long-term deal, says the current state of the free-agent market is "sad."

A UCSF study of human and mouse pancreatic tissue suggests a new origin story for type 1 diabetes.

The Cleveland Indians and two-time All-Star reliever Tyler Clippard have agreed to terms on a minor league contract.

Bullpen consistency can be the difference between a pennant and going home early. Who's best at nailing down wins and protecting leads?

"It's dumb because they have us in last place." Winners of an average of 97 games over the past four years, here's what the Cubs really think about a projection that has them winning 79 games.

With his awful 2018 season now in his rearview mirror, the Yankees' catcher might be ready to resume mashing.

Manny Machado has yet to formally sign his 10-year, $300 million contract with the San Diego Padres, but that didn't stop the team's store at Petco Park from briefly having his No. 13 jerseys available for sale on Wednesday.

Buster Posey most likely will not catch in any spring training games until early March, Giants manager Bruce Bochy said Wednesday.

A program offering group support, acupuncture, mindfulness, massage and gentle exercise may help prevent patients on prescription opioids from spiraling down to drug misuse, overdose and death.

Troy Tulowitzki, who missed all of last season with the Blue Jays due to injuries, says he's healthy and excited about chasing a World Series title with the Yankees.

The Detroit Tigers and veteran infielder Josh Harrison have agreed to a one-year deal, a source confirmed to ESPN's Jeff Passan.

Jed Lowrie will get an MRI after experiencing pain in the back of his knee while running.

Tim Anderson says Manny Machado 'might have' missed the boat by choosing the Padres over the White Sox.

The Baltimore Orioles have a season win total of 59.5, while the Yankees are at 96.5. Here are the odds you need to know for all 30 MLB teams.

Ronald D. Vale, PhD, professor of cellular and molecular pharmacology at UCSF, has been named executive director of the Janelia Research Campus of the Howard Hughes Medical Institute and an HHMI vice president, effective in early 2020.

San Diego made a surprising free-agent splash for the second consecutive winter. But can the Padres surround Manny Machado and Eric Hosmer with a championship-level roster?