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Boston's title defense is over and its front office is in flux. And with their biggest star approaching his walk year, the Red Sox have a ton of work to do this winter and beyond.

It doesn't get much better than two of baseball's bitter rivals squaring off with a playoff spot up for grabs. We look at the matchup from both sides.

Stephen Vogt hit a two-run homer and the Giants beat the Red Sox 11-3 on Wednesday night, giving Bruce Bochy his 2,000th career victory as a manager in the majors.

Giancarlo Stanton, who had been out since June 25 with a knee injury, went 1-for-3 with a double in his return, but New York fell 3-2 to the Angels and must wait at least another day to clinch the AL East.

Astros right-hander Gerrit Cole struck out Shin-Soo Choo in the sixth inning Wednesday night for his 300th strikeout of the season. He's the 18th major leaguer since 1900 to strike out at least 300 in a season.

Stephen Vogt hit a two-run homer and the Giants beat the Red Sox 11-3 on Wednesday night, giving Bruce Bochy his 2,000th career victory as a manager in the majors.

Yankees slugger Giancarlo Stanton, who had been out since June 25 with a right knee injury, went 1-for-3 with a double in his long-awaited return, but New York fell 3-2 to the Angels.

The Drug Enforcement Administration is investigating where Angels pitcher Tyler Skaggs obtained the drugs that were in his system at the time of his July 1 death in Southlake, Texas, sources with knowledge of the investigation told Outside the Lines.

Red Sox manager Alex Cora said that David Price won't pitch again this season due to a cyst in his wrist that has limited him to a single two-inning start since early August.

Astros manager A.J. Hinch said Wednesday that Aaron Sanchez's recovery from shoulder surgery likely will extend into next season.

Venezuela's winter baseball league has postponed play for nearly three weeks after MLB banned its players from playing in the league.

The joint donation from MLB and its union will be divided into $70,000 donations to Project Hope, Water Mission and SBP.

According to a criminal complaint released by Pennsylvania State Police, Pirates closer Felipe Vazquez admitted that he tried to have sex with a 13-year-old girl.

With just 10 games remaining in the regular season, Yankees slugger Giancarlo Stanton has returned to the starting lineup after recovering from a ligament strain in his right knee.

Mad Max in a winner-take-all game seems like a no-brainer. But Washington might have an even better option.

Showing off ace-level stuff, Luis Severino just made himself a major factor in the Bombers' October outlook.

Without a full rebuild or a big budget, the A's are in the postseason picture again. Almost two decades after Moneyball, how do they keep doing it?

Here's which teams at the top of the standings could punch their October tickets soon and how the playoff field looks right now.

Giants outfielder Mike Yastrzemski, the grandson of Red Sox great Carl Yastrzemski, said playing at Fenway on Tuesday "isn't just special for me. This is special for anyone who saw my grandfather play."

In a game that featured 50 players overall, the Giants and Red Sox tied a major league record in Tuesday night's game by combining to use 24 pitchers, including a record-tying 13 from the Giants.