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White Sox manager Tony La Russa is out indefinitely with an unspecified medical issue, a source confirmed to ESPN.

The Rays placed All-Star left-hander Shane McClanahan on the 15-day injured list Wednesday, a day after he was scratched from his start because of left shoulder impingement.

Lee Thomas, an All-Star player who eventually became the architect of the 1993 NL champion Philadelphia Phillies, has died. He was 86.

The San Diego Padres and San Francisco Giants will play in the first regular-season Major League Baseball games in Mexico City next year, three seasons after the first scheduled matchup there was canceled because of the COVID-19 pandemic.

The Orioles have promoted top infield prospect Gunnar Henderson to the majors and signed veteran first baseman Jesus Aguilar as they continue their push for a postseason spot.

Why did the M's hand a 21-year-old rookie an unprecedented nine-figure deal? Because Seattle saw something special.

Fernando Tatis Jr. had to postpone a scheduled shoulder surgery because he has strep throat, the latest wrinkle in what's been a turbulent season for the San Diego Padres shortstop.

New York Yankees veteran starter Jameson Taillon was diagnosed with a right forearm contusion after leaving his start against the Los Angeles Angels on Tuesday night, but X-rays for a possible fracture came back negative, the team said.

Timmy Trumpet tweeted he'd back at Citi Field on Wednesday night, hoping again to play Edwin Díaz's wildly popular entrance song in person when the Mets hosted the Dodgers.

Rays All-Star Shane McClanahan (shoulder) was a late scratch in his scheduled start against the Marlins on Tuesday.

The White Sox said manager Tony La Russa would miss Tuesday night's game on the recommendation of his doctors and would undergo further testing Wednesday.

Three-time NL Cy Young Award winner Clayton Kershaw, who hasn't pitched since Aug. 4 due to back pain, will be activated off the injured list and start against the New York Mets on Thursday.

The Washington Nationals are placing rookie right-hander Cade Cavalli on the injured list with right shoulder inflammation, and manager Dave Martinez said he will be shut down for two weeks and then re-evaluated.

Mets pitcher Carlos Carrasco, who has been on the injured list with an oblique strain since Aug. 1, may return to the starting rotation by the end of the week, manager Buck Showalter said.

MLBPA head Tony Clark is confident that at least 30% of minor league players will sign recently distributed union authorization cards in the coming days and weeks, paving the way for thousands more players to potentially join the organization.

The Houston Astros have placed staff ace Justin Verlander on the injured list after he suffered a right calf injury on Sunday against the Baltimore Orioles.

The Diamondbacks exercised their 2023 club option for manager Torey Lovullo, who already has eight more wins this season than last year's 52-110 record.

A Brewers fan might have had his heartbroken Monday night due to a video board message. Milwaukee did its best to cheer him up with a win.

The owners of the two best records in the NL are set to square off in Queens. We break down how much an August series could mean for a possible NLCS meeting.

Corbin Carroll, one of the game's consensus top prospects, hit a go-ahead, two-run double in his big league debut and the Diamondbacks climbed out of an early seven-run hole against the Phillies for the biggest comeback win in franchise history.