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Colorado Rockies minor league third baseman Colton Welker tested positive for a performance-enhancing substance and was suspended 80 games by the commissioner's office Thursday.

Jose Altuve responded to jeering fans by marking his 31st birthday with a go-ahead, three-run homer off Chad Green in the eighth inning, and the Astros beat the Yankees 7-4 Thursday to avoid a three-game sweep.

The Angels designated Albert Pujols for assignment Thursday, cutting ties with the slugger who signed a 10-year, $240 million contract with the franchise in 2011.

George Springer, who returned to the IL on Wednesday after aggravating his strained right quadriceps, is "frustrated," GM Ross Atkins said, and likely will be out longer than 10 days.

The New York Mets have shifted pitcher Carlos Carrasco to the 60-day injured list, pushing his potential season debut until late May at the earliest.

Del Crandall, a star catcher who played on two Milwaukee Braves teams that reached the World Series in the 1950s before managing the Brewers and Mariners, has died. He was 91.

Mays could do it all -- hit, run, throw. But how do you explain Mays, who turns 90 on Thursday, to this generation?

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The Orioles' John Means pitched a no-hitter against the Mariners on Wednesday, facing the minimum 27 batters, but because a runner reached first on a wild pitch after striking out, it's not a perfect game.

Chicago White Sox manager Tony La Russa says he didn't fully know the extra-inning rule, which would have allowed him to avoid using closer Liam Hendriks as a baserunner against the Cincinnati Reds on Wednesday.

Reds slugger Joey Votto will miss about a month after being hit on the left thumb by a pitch from White Sox hurler Dallas Keuchel, manager David Bell said.

Ray Miller, who served as pitching coach of the Orioles over several stints and who served as manager of the team as well as of the Twins, has died at the age of 76, the team announced.

Second baseman Rougned Odor was put on the 10-day injured list by the Yankees with a sprained left knee on Wednesday.

Veteran reliever Pedro Strop has elected free agency after spending most of this season at the Chicago Cubs' alternate site.

New York Mets pitcher Jacob deGrom could return to the mound on Sunday against the Arizona Diamondbacks.

After dealing with depression and self-doubt for years, Drew Robinson reached a crisis point in April 2020. But what was almost the end of his story turned out to be the start of another.

Drew Robinson, who lost his right eye in a suicide attempt in 2020, has made the opening day roster for the San Francisco Giants' Triple-A affiliate, the Sacramento River Cats, and could play as soon as Thursday.

The Blue Jays, who haven't played a game in Toronto since the 2019 season due to Canadian government restrictions during the coronavirus pandemic, will again set up shop in Buffalo after spending the first two months of the 2021 season in Florida.

Minor league baseball drew 103,483 fans for 47 games on its opening day after missing the 2020 season because of the coronavirus pandemic.

The Blue Jays, who haven't played a game in Toronto since the 2019 season due to Canadian government restrictions during the coronavirus pandemic, will again set up shop in Buffalo after spending the first two months of the 2021 season in Florida.