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Trayce Thompson belted a grand slam in his first at-bat of the season, and didn't stop there.

Jack Flaherty survived a career-high seven walks and a hit batter, managing to still throw five no-hit innings as the Cardinals beat the Blue Jays 4-1 on Saturday.

The Mariners placed starting pitcher Robbie Ray on the 15-day injured list with a left flexor strain after he took the loss in his first start of the season Friday against the Guardians.

Brewers third baseman Luis Urías will miss the next 6 to 8 weeks with what manager Craig Counsell called a "significant" hamstring strain. Milwaukee is calling up outfield prospect Joey Wiemer.

Anthony Rendon said he couldn't comment on the video that showed him confronting and taking a swipe at an Athletics fan on Opening Day.

Dusty Baker & Co. were presented their 2022 World Series rings in a pregame ceremony.

The Padres agreed with second baseman Jake Cronenworth on a seven-year extension that will keep him in San Diego through the 2030 season, a source confirmed to ESPN.

MLB is investigating a confrontation between Angels third baseman Anthony Rendon and an Athletics fan at Thursday's season opener in Oakland.

The San Francisco Giants have agreed to a minor league deal with two-time All-Star catcher Gary Sanchez, according to a report.

Everything you need to know to place your MLB bets and set your fantasy baseball lineups for Saturday, April 1.

Minor leaguers ratified their first collective bargaining agreement with Major League Baseball, with the MLBPA saying more than 99% of players who cast ballots approved the deal.

How new rule changes will affect sportsbook's and bettors' approaches to wagering.

Angels two-way star Shohei Ohtani's decision to call his own game through a PitchCom device Thursday night against Oakland is directly related to the pitch clock.

Jacob deGrom said he was 'not thrilled' after lasting just 3.2 innings, giving up five runs on six hits in his first start as a Texas Ranger against the Philadelphia Phillies on Thursday.

St. Louis Cardinals catcher Willson Contreras left Thursday's Opening Day contest against the visiting Toronto Blue Jays in the top of the eighth inning after a 103 mph pitch glanced off his knee.

Rockies closer Daniel Bard will open the season on the injured list because of anxiety.

Orioles catcher Adley Rutschman became the first catcher with five hits on Opening Day since at least 1900, going 5-for-5 with a homer and four RBIs in Baltimore's 10-9 victory over the Red Sox.

Cubs starter Marcus Stroman became the first pitcher to be called for a pitch clock violation while Boston Red Sox third baseman Rafael Devers became the first player to strike out on a pitch clock violation on Opening Day on Thursday.

The Washington Nationals have placed pitcher Stephen Strasburg on the 60-day injured list as he continues to recover from an operation for thoracic outlet syndrome.

Everything you need to know to place your MLB bets and set your fantasy baseball lineups for Friday, March 31.