|Hickman||Prochaska||Hickman, N. J., Prochaska, J. J., & Dunn, L. B. (2011) Screening for research consent capacity in the inpatient psychiatry setting. Journal of Empirical Research on Human Research Ethics, 6(3):65-72.|
|Dunn||Kaup, A. R., Dunn, L. B., Saks, E. R., Jeste, D. V., & Palmer, B. W. (2011) Decisional capacity and consent for schizophrenia research. IRB: Ethics and Human Research, 33(4):1-9.|
| Hall||Hall, S., Humfleet, G., Muñoz, R., Reus, V., Prochaska, J., & Robbins, J. (2011) Using extended cognitive behavioral treatment and medication to treat dependent smokers. American Journal of Public Health. Published online ahead of print June 7, 2011: e1-e8. doi:10.2105/AJPH.2010.300084. PMID: 21653904|
|Delucchi||Hendricks, P. S., Delucchi, K. L., & Hall, S. M. (2010) Mechanisms of change in extended cognitive behavioral treatment for tobacco dependence. Drug and Alcohol Dependence, 109, 114-119. |
|Hamilton||Hamilton, S. P. (2011) A new lead from genetic studies in depressed siblings: Assessing studies of chromosome 3. American Journal of Psychiatry, 168(8):783-789.|
|Jones||Herbst, E. D., Harris, D. S., Everhart, E. T., Mendelson, J., Jacob, P., & Jones, R. T. (2011) Cocaethylene formation following ethanol and cocaine administration by different routes. Experimental and Clinical Psychopharmacology, 19(2):95-104. PMID: 21463066|
|Satre||Mackin||Satre, D. D., Sterling, S. A.,Mackin, R. S., & Weisner, C. (2011) Patterns of alcohol and drug use among depressed older adults seeking outpatient psychiatric services. American Journal of Geriatric Psychiatry, 19(8):695-703.|
|Weisner||Eisendrath||Satre, D. D., Chi, F. W., Eisendrath, S., & Weisner, C. (2011) Subdiagnostic alcohol use by depressed men and women seeking outpatient psychiatric services: Consumption patterns and motivation to reduce drinking. Alcoholism: Clinical and Experimental Research, 35(4):695-702.|
|Voglmaier||Zhaolin, H., Leal-Ortiz, S., Foss, S. M., Waites, C. L., Garner, C. C., Voglmaier, S. M., & Edwards. R. H. (20111) v-SNARE composition distinguishes synaptic vesicle pools. Neuron, 71(3):474-487. |
- A fundamental new discovery about how nerve cells in the brain store and release tiny sacs filled with chemicals may radically alter the way scientists think about neurotransmission.
| von Zastrow||Kotowski, S. J., Hopf, F. W., Seif, T., Bonci, A., & von Zastrow, M. (2011) Endocytosis promotes rapid dopaminergic signaling. Neuron, 71(2):278-90. |
- This paper shows that the machinery that mediates removal of dopamine receptors from the surface of neurons after dopamine exposure enhances the acute signaling response. It also shows that this link between endocytic and signaling machineries is essential for rapid dopamine-induced control in neuronal excitability in the basal ganglia—it is this type of signaling that communicates the salience of normally rewarding environmental cues, and mediates the pathologically reinforcing effects of addictive drugs. The study involves neural imaging, biochemical and electrophysiological approaches applied to cultured cells and brain slice preparations.
Lau, E. K., Trester-Zedlitz, M., Trinidad, J. C., Kotowski, S. J., Krutchinsky, A. N., Burlingame, A. L., & von Zastrow, M. (2011) Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection. Science Signaling, in press.
- This paper defines a biochemical basis for how the addictive opiate drug morphine produces a different regulatory consequence than endogenously produced opioid peptides following binding to mu-opioid receptors. The ability of morphine to produce differential effects is of great potential importance to how addictive drugs work at the most fundamental level, but defining whether or not there is a difference in regulation at the level of individual opioid receptors has been the source of considerable confusion and controversy. This study largely (we think) settles the matter, by defining a clear biochemical basis for agonist-selective drug action occurring at the level of individual opioid receptors. The study uses cultured neurons, together with various biochemical and mass spectrometry-based analytical methods.
|Yaffe||Yaffe, K., Laffan, A. M., Harrison, S. L., Redline, S., Spira, A. P., Ensrud, K. E., Ancoli-Israel, S., & Stone, K. L. (2011) Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. Journal of the American Medical Association, 306(6):613-619.|