brainLENS Seminar Series


4/28/2014, 1:00 - 2:00 p.m.


Parnassus LP-371


Fumiko Hoeft - Contact Information


Name: Olga Tymofiyeva, PhD

Title: Post-Doctoral Scholar

Institution: UCSF Dept. of Radiology & Biomedical Imaging

Presentation: Structural MRI Connectome in Development: Challenges of the Changing Brain


MRI connectomics is an emerging approach to studying the brain as a network of interconnected brain regions. Understanding and mapping the development of the MRI connectome may offer new insights into the development of brain connectivity and plasticity, ultimately leading to more effective diagnosis and treatment of developmental disorders. However, construction of the structural connectome in the neonate is made difficult by the technical obstacles associated with performing MRI in this age group and by the challenge of defining normal anatomical landmarks in the rapidly developing brain. Our group has developed an atlas-free approach to longitudinally study the structural connectome (without the need for anatomical priors) using diffusion MRI, equal-area parcellation of the cortex and co-registration in network space. Using this approach, distinct patterns of increasing network integration and decreasing segregation are observed, along with a modular architecture present in the brain from the first days of life. 

About the speaker:

Dr. Olga Tymofiyeva is a Post-doctoral scholar who has been working in Dr. Duan Xu's lab, UCSF Radiology & Biomedical Imaging Department, since May 2010. She holds her degrees in Physics (PhD, University of Wuerzburg, Germany) and Electrical Engineering (MSc, Karlsruhe University of Applied Sciences, Germany and BSc, NTUU "KPI", Kyiv, Ukraine). Olga's current research interest lies in using MRI to assess the structural connectivity of the newborn brain. 


Leadership in research, education, psychiatric care and public service