Schizophrenia – Optimizing Cognitive Remediation Outcomes in Schizophrenia
Description This study will investigate whether computerized training might help people with schizophrenia lessen their symptoms and learn new thinking and problem-solving skills. All participants will receive a baseline evaluation of clinical, neurocognitive, and quality of life measures.
Study Design All participants will complete either computer-based training exercises or play control graphics-based computer games for 60 minutes per day, five days per week, for eight weeks. (This is fun!) After these eight weeks, participants will undergo a second evaluation of clinical, neurocognitive, and quality of life variables. They will have the option of continuing with a different type of training for another 8 weeks. After these 8 weeks, participants will undergo a third evaluation. Six months after completion of the intervention, each participant will be asked to return to the laboratory for a fourth evaluation of clinical, quality of life, and neurocognitive measures.
End Date 12/1/2013
- 18-60 years old
- diagnosis of schizophrenia or schizoaffective disorder
- achieved clinical stability, defined as outpatient status for at least three months prior to study participation
- stable doses of psychiatric medications for at least one month prior to study participation
- in good general physical health
- use English as first language
Persons not eligible:
- history of neurological disorders
- using mood stabilizers and/or on antidepressants
- history of psychoactive substance abuse in the past six months
Payment Participants may receive up to $800 for the 20 weeks of participation that will include initial assessments, sessions of the computerized training program or the computer games, and final assessments.